One Medical - Mission Bay — Mission Bay, San Francisco, CA
499 Illinois St, San Francisco, CA 94158
Hours of Operation
Services Available
Accepted Insurance
About This Location
One Medical - Mission Bay is part of One Medical, a tech-forward primary care network owned by Amazon that offers same-day appointments, virtual visits, and in-person walk-in care across the Bay Area for its members. One Medical operates a membership-based model (~$200/year) where members get 24/7 virtual care, same-day or next-day appointments, and integrated urgent care at any One Medical office in the country. Services include care for minor illnesses, injuries, infections, skin conditions, UTIs, travel medicine, vaccinations, and physicals. The clinic accepts most major commercial insurance plans for the visit (insurance covers the medical care, membership is separate). Located in Mission Bay, the clinic operates 8:00 AM – 7:00 PM on weekdays. One Medical's app lets members message their care team, book appointments, and access records with minimal friction.
About Mission Bay
Mission Bay is a 300-acre mixed-use redevelopment district south of SoMa, transformed from industrial rail yards into one of the largest urban rebuilds in the U.S. It's anchored by UCSF's Mission Bay campus (including the Benioff Children's Hospital), Oracle Park, Chase Center, and significant residential towers. The neighborhood is young, tech-heavy, and transit-accessible, making it one of the densest healthcare-and-tech employment clusters in the western U.S.
Frequently Asked Questions
Do I need to be a One Medical member to be seen here?
Yes — One Medical operates a membership model (~$200/year for individuals) that provides access to all One Medical offices, 24/7 virtual care, and a premium app experience. Non-members typically can't book appointments or walk in.
Does insurance cover my visit?
Insurance covers the medical care portion of your visit at the same rates as any in-network provider. The membership fee is separate and not insurance-covered (some Amazon Prime accounts may include free or discounted One Medical membership). Most major commercial insurance plans and Medicare are accepted.
What's the difference between One Medical and urgent care?
One Medical is primarily primary care with urgent care capabilities — so if you're already a member, your urgent visit is integrated with your full primary care record. If you're not a member, traditional urgent care (Carbon, AFC, CityHealth, etc.) is more accessible.
Can I schedule same-day at One Medical - Mission Bay?
Yes — same-day or next-day appointments are typically available through the One Medical app. Virtual visits are available 24/7 for members, which handles many common conditions without an in-person visit.
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